New versions of Metal Gear Solid, Pro Evolution Soccer, Contra and Frogger will be among the first few Konami titles to appear on the high-tech handheld, which displays stereoscopic 3D visuals without the need for special glasses.
The 3DS version of Metal Gear Solid: Snake Eater has already been showcased at industry events such as E3 and the Tokyo Game Show, wowing attendees with its home console-quality visuals.
It is a remake of the Cold War-set PlayStation 2 classic of the same name, enhanced by eye-popping 3D effects and setpieces.
Football fans will be happy to see an all-new version of PES on the way for the system, while fresh instalments of Contra and Frogger will appeal to lovers of the arcade originals.
Konami's Kunio Neo said: "We cannot wait to share more news in the coming months."