The groundbreaking title sets itself apart from previous music games by allowing players to plug in actual electric guitars to use as controllers, with the game offering a crash course in real guitar-playing skills.
Featuring tracks from the likes of Blur, David Bowie, the Rolling Stones, Nirvana, Muse and many more artists besides, Rocksmith has a flexible difficulty curve and teaches users how to play guitar in a fun and engaging way.
The game can be purchased on its own or in a special bundle that includes a fully-functioning Epiphone Les Paul Junior guitar, created by iconic instrument manufacturer Gibson.
Henry Juszkiewicz, chairman and chief executive officer of Gibson, said: "Rocksmith provides a new and exciting opportunity for fans of all musical abilities to pursue their dreams - and actually learn how to play."
The game has been available in the US since October 2011 and has proven a critically acclaimed success, with the UK version set to contain bonus content not seen in the American release.