Speaking to Eurogamer, Epic's vice-president Mark Rein said he believes the innovative system and its revolutionary tablet controller will be a big success when Nintendo unleashes the device at the end of 2012.
Mr Rein praised the high-definition graphical capabilities of the system, suggesting that Epic's Unreal Engine 3 technology can be used to deliver visually stunning Wii U games.
However, the Wii U's controller remains its most talked-about feature, offering a huge touchscreen interface and a full complement of analogue sticks, buttons and triggers, as well as the ability to stream games straight from console to controller.
Mr Rein said he has played the Wii U version of Batman: Arkham City and was full of praise for the possibilities offered by the control device, adding that he expects further revelations at this year's E3 trade show.
"I think we've yet to really see what the Wii U can do and I think at E3 this year they're going to shock us," he said.